Sometimes the device even though listed in the Device Manager is not accessible by the Windows. This is when Windows cannot gain access to this hardware device (Code 46) is marked in the device status. In case you got this error message as a pop-up, it usually means that some process was trying to access it, but failed because the system is shutting down.

Good news is that you do not have to resolve this issue, but when you restart the system, the application or process will be able to access it again and get its work done.

Note: This error code is only set when Driver Verifier is enabled and all applications have already been shut down.